New Treatments | Depression: Physiological cause; Treat with magnesiumglycinate
Diseases > Depression
One out of 20 people is depressive
A depression is horrible. It's not possible for friends to imagine how it feels.
All plesure and joy are being sucked out of a depressive person. If it's not treated well, it can
eventually even suck out the person's life.
It's very common in the Western world. Every moment, about 1 out of 20 people (5% of the population) are depressive. Please note that a depression is nothing like the ocassional temporary moments of feeling bad after problems in your life. In healthy people good and bad experiences and feelings come and go. In depressive people, on the other hand, these bad feelings keep on lasting for indefinite times. During these periods, the depressed person isn't able to enjoy any facet of life.
Please note that the discovery and the research was all done by George Eby. This article is just a short summary of his findings.
Please read his full, wonderful article and his testimonial here: George Eby's site.
Below are also some of my (Ed's) personal experiences:
When I discovered in 2001 that I suffered from a magnesium deficiency, I started to supplement magnesium by taking magnesium-glycinate tablets. I was pleasantly surprised by the broad range of effects this had on my health. I used to feel really bad when I was hungry. After I started to use magnesium, I feel in my stomach I'm hungry, but the feeling is restricted to my stomach. My mood isn't affected anymore. After doing some experiments, I discovered I could even manage without food for eight hours (Please note: I have hypoglycemia).
My heart arhithmia problems disappeared instantly, my muscle spasms disappeared, I was feeling much more positive and energetic. I enjoyed life better and my sleep improved also. Fascinated by these impressive results, I studied magnesium further.
Magnesium: A very essential mineral
I've studied many articles and studies. I learned that magnesium is a very essential
mineral in human health. The recomended daily dosage is 350 mg per day. The western
diet, alas, doesn't contain enough magnesium, only 200 mg at best. This is because
we eat too many refined foods which are deprived of essential minerals and because
the vegetables grow on soil that lacks minerals.
The FDA even wonders if they shouldn't increase the recomended daily dosage to 800-900 mg per day.
High Carbohydrate diet can cause magnesium deficiency
Studies [Barbagallo, Renick 1994] show that high blood glucose levels causes the flushing of different minerals, among which magnesium. Calcium, on the other hand, is not affected. This poses a problem, because calcium is the antagonist of magnesium. A mineral antagonist "fights" some other mineral, meaning that high calcium levels will cause lower magensium levels. Check all mineral interrelationships. After eating a high-carbohydrate diet for several years, a magnesium deficiency will be inevitable. This won't show up on the blood magnesium tests, because most magnesium is stored inside the cells, intracellular.
A magnesium deficiency, hypomagnesemia, can cause many problems, among which:
Relation between hypomagnesemia and depression
Several studies show without doubt that there is a definite relation between magnesium deficiency and depression
Low magnesium status in patients that try to commit suicide
Patients who had made suicide attempts (by using either violent or nonviolent means) had significantly lower mean CSF magnesium level irrespective of the diagnosis.
Ratio Calcium/Magnesium is significantly elevated in depressive patients
Serum and CSF Ca/Mg ratios were found to be elevated in the depressed patients compared with the controls
Magnesium suppletion causes significant improvement in manic patients
Ten patients with severe, therapy-resistant manic agitation received magnesium sulphate infusions.
Seven (of 10) patients showed a marked improvement in the Clinical Global Impression scale
Depression: Not a psychological cause, but a physiological cause !
I dare to propose that most depressive people have a simple deficiency of magnesium that causes their disease: A physiological
cause instead of psychological cause.
If this is correct, all session with shrinks can be considered worthless. A simple magnesium supplement
can make the depression disappear fully in only two days. It is however important to take the right supplement, because
there are many forms of magnesium and most of them are absorbed very poorly or contain ingredients that acts as excitotoxins (poison to the neurons in your brain).
The one and only effective supplement (until now) is the Magnesium-glycinate supplement, produced by Carlson Labaratories.
Please don't use the Solgar's magnesium-glycinate supplement (no offence, Solgar has other great products), since it also contains considerate amounts
of calcium, which will act as an antagonist on magnesium.
The proof is in the eatingOn George site van George EbyEby's site from Texas USA, you will find his findings on using magnesium-glycinate for treating his severe depression. Below some quotes:
Another important factor: STRESS
Besides the causes you can read above, there is another possible cause of a
magnesium deficiency which then causes a depression: STRESS.
Physical (exhaustion, heat, cold, trauma, burns) and emotional (pain, fear, excitation) stress cause the secretion of several hormones into the blood. These hormones (adrenalin amongst others) cause the excretion of magnesium. When this stress prolongs, a vicious cycle starts because a magnesium deficiency causes a greater release of hormones, which in turn cause a greater excretion of magnesium. You get stressed easier and easier and more and more magnesium gets excreted each time.
A good REM-sleep is important for recovery
Another vicious cycle: For good REM-sleep (Rapid Eye Movement, the deep sleep in which the immune system recovers) magnesium is needed. And on the other hand, Without a decent REM-sleep more magnesium is excreted (through upset hormones because of lack of REM-sleep). A good tip is to use 400mg of (elemental) magnesium-glycinate before sleep: This improves the REM-sleep.
To prevent future depressions, we should try to thwart the causes:
Below is a review of the causes:
The connection with estrogen, the female hormone
Postnatal depression, depression during menopause and depression after stopping the anti-conception pills all have the same cause.
These three situations have in common a decrease of estrogenvalues in the blood. After pregnancy
the estrogen levels decrease, during menopause the estrogen levels decrease and after quiting the anti-conception pill the estrogen levels drop to normal levels (during pregnancy and anti-conception
they are increased).
Estrogen causes a higher absorption and use of magnesium and zinc. Estrogen is normally associated with pregnancy. During pregnancy the body needs more minerals en estrogen takes care of the higher absorption. The estrogen enables a female to get just enough magnesium out of a low-magnesium diet. When the estrogen levels drop, the magnesium absorption drops and hypomagnesemia (magnesium deficiency) is the result. This can then cause a severe depression or diabetes or hypoglycemia or many other problems.
The anti-conception pill is often used to heal acne. Possibly this works because the estrogen increases absorption of zinc, which is essential for a healthy skin.
George Eby's Rules for Success
After much e-mail correspondence with people not finding success with "magnesium" as rapidly as they wanted, we (they working with me) have found that their personal choices and long-standing dietary habits contributed to failures. If the following rules for success were followed, success in defeating magnesium-deficiency mental health problems was usually theirs:
Please review each of the above links at least once.
This is what a bottle of Carlson Magnesium Glycinate looks like. You should be able to find them at your favorite health food store. If you prefer to order Carlson's Magnesium glycinate, click this graphic of Carlson Magnesium Glycinate to go to George Eby's order form.
90% of what's written down here, is taken from George Eby's site. The NewTreatments article only summarises George's wonderful work. The only thing I've added is the relation with carbohydrate consumption and some details on estrogen.
Revision: May, 29th 2002, 2nd December, 30th 2002, Ed