stress is associated with migraines
stress can lead to loss of magnesium
calcium channel blockers prevent some migraines
magnesium is a natural calcium channel blocker
spreading cortical depression (SCD) is implicated in some migraines
high leveles of magnesium inhibit SCD
migraine patients have high platelet aggregability
magnesium can suppress platelet aggregability
These clues suggest that magnesium deficiency may play a role in some kinds of migraine headache; a hypothesis which did not exist in the literature at the time Swanson found these links. The hypothesis has to be tested via non-textual means, but the important point is that a new, potentially plausible medical hypothesis was derived from a combination of text fragments and the explorer's medical expertise. (According to swanson91, subsequent study found support for the magnesium-migraine hypothesis Ramadan et al.1989.)''
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